We argue that the most‐promising area of clinical application of microarrays in the foreseeable future is the diagnostics and monitoring of infectious diseases. Microarrays for the detection and characterization of human pathogens have already found their way into clinical practice in some countries. After discussing the persistent, yet often underestimated, importance of infectious diseases for public health, we consider the technologies that are best suited for the detection and clinical investigation of pathogens. Clinical application of microarray technologies for the detection (...) of mycobacteria, Bacillus anthracis, HIV, hepatitis and influenza viruses, and other major pathogens, as well as the analysis of their drug‐resistance patterns, illustrate our main thesis. BioEssays 30:673–682, 2008. © 2008 Wiley Periodicals, Inc. (shrink)

[1]Aldanov, M. A. [i dr.] Religīoznyi︠a︡ i obshchestvennyi︠a︡ iskanīi︠a︡.--[2]Melgunov, S. P. N. V. Chaĭkovskīĭ v gody grazhdanskoĭ voĭny.

About 130 languages are currently spoken in the USSR. These languages differ considerably in their numbers of speakers, social status, scope and viability. Our primary interest in this paper will be with those languages that are in extreme danger of extinction in the near future.

The article analyzes the problem of the correlation of morality and ideology. The author believes that the distinction between morality and ideology can be made only at the level of their genealogy: if ideology is a socio-cultural product, then morality is rooted in human nature, in "moral intuitions", which medieval scholastic philosophy called synderesis. In modern ethics, synderesis can be identified with the neurophysiological prerequisites of morality. Opponents of this approach argue that, firstly, it excludes free will, and secondly, it (...) does not explain the content of moral values and norms in any way. The author of the article criticizes these statements and offers his original theory of synderesis. The article draws an analogy between ethics and intuitionistic mathematics, which considers mathematical objects as the results of intellectual construction based on initial intuitions. Ethical objects should also be considered as constructions based on innate intuitions. Moral intuitions do not exclude free will, since they rely on rationality inherent in our nature, the main property of which is the ability to make decisions regardless of external stimuli and internal states. In addition, these intuitions influence the content of our norms, as they are the "operators" of their construction and are included in the "final product". (shrink)

kn. 1. Sushchnostnoe vosprii︠a︡tie slova.

This book is not only a major twentieth-century contribution to Dostoevsky’s studies, but also one of the most important theories of the novel produced in our century. As a modern reinterpretation of poetics, it bears comparison with Aristotle.“Bakhtin’s statement on the dialogical nature of artistic creation, and his differentiation of this from a history of monological commentary, is profoundly original and illuminating. This is a classic work on Dostoevsky and a statement of importance to critical theory.” Edward Wasiolek“Concentrating on the (...) particular features of ‘Dostoevskian discourse,’ how Dostoevsky structures a hero and a plot, and what it means to write dialogically, Bakhtin concludes with a major theoretical statement on dialogue as a category of language. One of the most important theories of the novel in this century.” The Bloomsbury Review. (shrink)

I. "Filosofskiĭ paroxod": k istorii voprosa -- II. Respressii i permanentnai︠a︡ ėmigrat︠s︡ii︠a︡ -- III. Overkili russkoĭ filosofii -- IV. Postsovetskiĭ period: v poiskakh identichnosti -- V. Vozvrashchenie "filosofskogo paroxoda" (2003) -- VI. "Filosofskie avtobusy" -- VII. Samolet-paroxod-"filosofskiĭ poezd" -- VIII. Afinskiĭ kongress: prikosnovenie k istorii (2013) -- IX. "Uchitʹsi︠a︡ bytʹ chelovekom": XXIV vsemirnyĭ filosofskiĭ kongress -- X. Mezhdu proshlym i budushchim.

This article discusses the foundation of ideas for Vyacheslav Ivanov’s interpretation of Pushkin’s poem. In The Gypsies, Ivanov sees a conflict between personal freedom and sobornost’ as revealed b...

The review surveys the main ideas discussed at the international scientific conference “Immanuel Kant and the ‘New Enlightenment’” hosted by the Immanuel Kant Baltic Federal University (IKBFU) in Kaliningrad on 20-22 April 2022. It was organised by IKBFU’s research unit Academia Kantiana with the support of the Petersburg Dialogue Forum. Speakers analysed the theses of the Report to the Club of Rome, Come on! Capitalism, Short-termism, Population and the Destruction of the Planet (2018), whose authors, Ernst Ulrich von Weizsäcker and (...) Anders Wijkman, initiated a call for a “new Enlightenment”. The participants compared these theses with Kant’s philosophical ideas and looked for an answer to the question whether Kant’s critical philosophy should be consigned to the “old” Enlightenment or whether it has real potential for the desired “new Enlightenment”. The summaries of papers and discussions are arranged in order of their presentation. The Conference has shown that Kant’s Enlightenment has not lost its relevance while the ideas of the “new Enlightenment” need to be further examined philosophically. (shrink)

One of the main trends of modern society is a marked increase of the theoretical interest to the sphere of mythology and the theory of myth. And in light of globalization approaches explicitly focus on the impact study of the regional aspects of social phenomena. In this regard, in regional studies of mythology appear attempts seen the myth city's as a socially formalized knowledge about the city or region, a strong regulatory and mobilization element in society, which is capable of (...) forming a regional entity and identity. A problem is in that every city has the own myths and specific municipal culture. It can be one of reasons of conflicts at co-operation of townspeople of different regions because all of us are inclined to identify itself with a sub-group on the sign of place of inhabitation, line of business or the world view. Thus, at all cities have different myths and symbols. We are inclined to see our city as city of the chosen townspeople, while other cities and regions are inhabited by demons and monsters. The article suggests to consider the city like a self-valuable phenomenon. The article submitted to scientific use of the term "the myth city's" which, the author's perspective is not identical to the concept of "myths of the city" and "Mythology of the city." also authors conducted analysis the history of the formation of the Donetsk's myth, identified the main stages of its formation, and conducted explication of its meaningful and functional characteristics. (shrink)

У статті оцінюється значення онтологічної та метафізичної проблематики у сучасному філософському дискурсі, критично аналізується концепція монографії Андрія Баумейстера «Буття і благо» та пропонується інтерпретація буття як ствердження реальності в соціально детермінованій дії.

У статті досліджується ситуація екзистенційної загрози, пов'язана з руйнуванням со­ціальної реальності. Зроблено припущення, що саме загроза існуванню тієї структурної частини реальності, яка походить від релігійно-міфологічних форм соціального буття, сприй-мається людиною як негайний привід до самозахисту. Навмисні зовнішні впливи на людську свідомість призводять до формування ерзац-реальностей, у яких "боротьба за цінності" є лише раціоналізованою формою дораціонального намагання зберегти ідентичність. Але саме пов'язаний з цим самозахистом стан розуму й дозволяє розпалювати конфлікти, подібні до східноукраїнського.

У статті проаналізовано вчення П'єра Абеляра в частині його впливу на виокремлення світської сфери знання з тотально релігійного середньовічного дискурсу. Схоластична теологія, творцем якої є Абеляр, розглядається автором статті як специфічний результат філософського мислення в граничних екзистенційних обставинах та маркер секулярних зрушень у середньовічній християнській культурі.

A collection of historical essays on human sexuality.

Монография предназначена для исследователей, изучающих вопросы философии, развития отечественной культуры, а также для преподавателей, студентов и аспирантов вузов.